CAS NO: | 2802-68-8/373-57-9 |
Formula: | BF3·CH3OH |
Appearance: | Colorless transparent liquid |
BF3Content: | ≥0.65% |
Moisture: | ≤0.2% |
The boron trifluoride methanol complex is utilized in a range of applications, including as a reagent for the deprotection of N-acetyl derivatives, such as acetylated amines of cyanine-type dyes, and as a starting material in the automated radiosynthesis of [18F]tetrafluoroborate.
Boron trifluoride methanol complex is also used to deprotect acetylated amines in cyanine dyes, yielding products with free amino groups, and to convert sulfur-containing phosphoramidates into the corresponding phosphate methyl ester.
As a powerful Lewis acid complex, the BF3 methanol complex plays a crucial role in both organic synthesis and industrial applications.
Similar to the BF3 THF complex, boron trifluoride methanol complex is known for its strong electron-accepting properties and is particularly effective in catalyzing a variety of chemical reactions, including esterifications, transesterifications, and polymerizations. Its ability to stabilize reaction intermediates and accelerate reaction rates makes it an invaluable tool for the efficient synthesis of complex organic molecules.
Additionally, the BF3 methanol complex is appreciated for its solubility in organic solvents and stability under diverse conditions, enhancing its practicality in both laboratory and industrial settings. It is also employed in the production of pharmaceuticals, fine chemicals, and advanced materials, highlighting its significant impact on modern chemical manufacturing and innovation.
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