The Boron Trifluoride Acetic Acid Complex is a specialized reagent used in esterification and alkylation processes. Its unique properties enhance reaction rates and yields, making it indispensable for the production of pharmaceuticals, fragrances, and other fine chemicals, ensuring high purity and efficiency.
| CAS NO: | 373-61-5 |
| Formula: | BF3· ( CH3COOH)2 |
| Appearance: | Colorless to light yellow transparent liquid |
| BF3 Content: ≥ 46% | 35-37% |
| Moisture: ≤0.2% | ≤ 0.2% |
| Density(20℃ )g/cm3: | 1.340-1.360 |
The Boron Trifluoride Acetic Acid Complex is a highly effective Lewis acid catalyst extensively used in organic synthesis and industrial chemistry. It is particularly valued for catalyzing a wide range of reactions, including esterifications, alkylations, and polymerizations.
The strong electron-accepting properties of boron trifluoride acetic acid complex facilitate the formation of reactive intermediates, enhancing reaction rates and improving yields. Known for its stability and solubility in various organic solvents, this complex is a versatile and practical choice for both laboratory and industrial applications.
In addition to its general catalytic roles, the boron trifluoride acetic acid complex is crucial in the Fries rearrangement reaction, an essential step in the total synthesis of furanaphin.
Boron trifluoride acetic acid complex also acts as a co-catalyst in the intramolecular amination of primary sulfonamides to form cyclic carbamates. This complex serves as a vital raw material and intermediate in the production of pharmaceuticals, agrochemicals, and dyestuffs.
Furthermore, boron trifluoride acetic acid complex is employed as a desilylating agent and has been used in the protodesilylation of the phenyl group, converting the dimethylphenylsilyl group into a hydroxyl group while retaining the configuration. Its broad applicability underscores its critical importance in advancing chemical research and industrial manufacturing.
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